Search on: NUCLEAR RECEPTOR CO REPRESSOR 2 
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Descriptor English:   Nuclear Receptor Co-Repressor 2 
Descriptor Spanish:   Co-Represor 2 de Receptor Nuclear 
Descriptor Portuguese:   Correpressor 2 de Receptor Nuclear 
Synonyms English:   SMRT Co-repressor
Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptor
T3 Receptor-associating Factor
TRAC Co-repressor
Co-repressor, SMRT
Co-repressor, TRAC
Nuclear Receptor Co Repressor 2
Receptor-associating Factor, T3
SMRT Co repressor
T3 Receptor associating Factor
TRAC Co repressor  
Tree Number:   D12.776.930.780.625.400
Definition English:   A nuclear co-repressor protein that shows specificity for RETINOIC ACID RECEPTORS and THYROID HORMONE RECEPTORS. The dissociation of this co-repressor from nuclear receptors is generally ligand-dependent, but can also occur by way of its phosphorylation by members of the MAP KINASE SIGNALING SYSTEM. The protein contains two nuclear receptor interaction domains and four repressor domains and is closely-related in structure to NUCLEAR RECEPTOR CO-REPRESSOR 1. 
History Note English:   2010(1995) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   53661 
Unique Identifier:   D056985 

Occurrence in VHL:
 

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